-We have set ourselves the goal of climate-neutral business operations along our entire value chain by 2040 -Scope 1 Target: Reduce Direct Emissions by 50% by 2030 (2020 Baseline) -Scope 2 Target: Reduce Indirect Emissions by 50% by 2030 (2020 Baseline) -Scope 3 Target: By 2030, we want to reduce our emissions along the entire value chain (Scope 3) by 52% in relation to our gross profit. (2020 Baseline) -Annually: Gross Scope 1 greenhouse gas emissions: 5.0% -2030: Gross Scope 1 greenhouse gas emissions: 913,561 tCO2eq -Annually: Gross market-based Scope 2 greenhouse gas emissions: 5.0% -2030: Gross market-based Scope 2 greenhouse gas emissions: 162,349 tCO2eq

-In addition, we are aiming to source 80% of our purchased electricity from renewable energies by 2030

-By the end of the decade, we want to achieve a circularity rate of 70% in our waste flows and improve our water intensity (per euro value added) by 50% -2030: We aim for 100% of our fiber-based packaging to use deforestation- free packaging -2030: We aim to design packaging that is 100% in line with our principals of circular product development -We are striving to reduce packaging weight by a total of 6,300 metric tons (SHRINK) by 2030 -unclear: By 2030, we aim to reduce potentially harmful residues in our wastewater to below the no- effect threshold -no target: 2030: Water efficiency (m3 per € million net sales): 396 -no target: We aim to reduce the packaging weight per sales unit by 10% by 2030 -no target: Aubonne: Through this, we expect to save 30,000 cubic meters per year from 2026 onwards

-For the year 2025, our objective is to cover 92% of our relevant supplier spend and 73% of our relevant suppliers with sustainability assessments

-To improve occupational safety, we aim to lower the lost time injury rate (LTIR) to below 1 by 2025 -Another core element of our health strategy is a mandatory training for managers to promote a health-oriented leadership culture. We aim to continuously improve the concepts and related materials we provide to managers for this purpose and plan to complete the rollout to 95% by the end of 2026

-Our aim is to achieve gender parity by the end of 2030 -2027: First management level of Merck KGaA below the Executive Board: 48.1% of positions held by women -2027: Second management level of Merck KGaA below the Executive Board: 35.8% of positions held by women -Therefore, by 2030, we want to increase the proportion of managers (middle and top management, role 4+) from underrepresented ethnic groups to 30% -We intend to increase the proportion of people from Asia, Latin America, and the Middle East and Africa (MEA) in management positions (middle and top management, role 4+) to 30% by 2030 -Another core element of our health strategy is a mandatory training for managers to promote a health-oriented leadership culture. We aim to continuously improve the concepts and related materials we provide to managers for this purpose and plan to complete the rollout to 95% by the end of 2026